BDBM449861 US10703741, Compound I-4::US10703741, Compound I-9

SMILES CN(C)C\C=C\C(=O)N[C@@H]1CNC[C@H]1NC(=O)c1ccc2n(C)c(nc2c1)-c1cc2cccnc2n1CC1CC1

InChI Key InChIKey=ZLBVSEGRTNQHQH-BJHKHANUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 449861   

TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM449861(US10703741, Compound I-4 | US10703741, Compound I-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM449861(US10703741, Compound I-4 | US10703741, Compound I-...)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM449861(US10703741, Compound I-4 | US10703741, Compound I-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM449861(US10703741, Compound I-4 | US10703741, Compound I-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent