BDBM450459 9H-Fluoren-9-ylmethyl 4-[3-[2- [(3,4-dichlorophenyl)methyl- methylamino]-2-oxoethyl]-4- oxoquinazolin-6-yl] piperazine-1-carboxylate (intermediate A-6) and propanoyl chloride ([CAS RN 79-03-8])::US10676446, Example 68
SMILES CCC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)N(C)Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1
InChI Key InChIKey=GATFYCBUGPWTKC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450459
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair