BDBM450459 9H-Fluoren-9-ylmethyl 4-[3-[2- [(3,4-dichlorophenyl)methyl- methylamino]-2-oxoethyl]-4- oxoquinazolin-6-yl] piperazine-1-carboxylate (intermediate A-6) and propanoyl chloride ([CAS RN 79-03-8])::US10676446, Example 68

SMILES CCC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)N(C)Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1

InChI Key InChIKey=GATFYCBUGPWTKC-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450459   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450459(9H-Fluoren-9-ylmethyl 4-[3-[2- [(3,4-dichloropheny...)
Affinity DataIC50:  4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent