BDBM450479 9H-Fluoren-9-ylmethyl 4-[3-[2-[(3,4-dichloro- phenyl)methyl- methylamino]-2- oxoethyl]-4- oxoquinazolin-6- yl]piperazine-1- carboxylate (intermediate A-6) and oxetane-3-carboxylic acid ([CAS RN 114012-41-8])::US10676446, Example 79
SMILES CN(Cc1ccc(Cl)c(Cl)c1)C(=O)Cn1cnc2ccc(cc2c1=O)N1CCN(CC1)C(=O)C1COC1
InChI Key InChIKey=WGLPIZUTVUNWDY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450479
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair