BDBM450504 9H-Fluoren-9- ylmethyl 4-[3- [2-[(3,4- dichlorophenyl) methylamino]-2- oxoethyl]-4- oxoquinazolin-6- yl]piperazine-1- carboxylale (intermediate A-5) and oxolane-3-::US10676446, Example 97
SMILES Clc1ccc(CNC(=O)Cn2cnc3ccc(cc3c2=O)N2CCN(CC3CCOC3)CC2)cc1Cl
InChI Key InChIKey=ZFFSYULCWWRFBM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450504
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair