BDBM450604 N-[(3-Chloro-4-cyanophenyl)methyl]-2-[8-fluoro-6-[1-(3-methoxypropanoyl)piperidin-4-yl]-4-oxoquinazolin-3-yl]-N-methylacetamide::US10676446, Example 188

SMILES COCCC(=O)N1CCC(CC1)c1cc(F)c2ncn(CC(=O)N(C)Cc3ccc(C#N)c(Cl)c3)c(=O)c2c1

InChI Key InChIKey=PXWIBTULLAMTPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450604   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450604(N-[(3-Chloro-4-cyanophenyl)methyl]-2-[8-fluoro-6-[...)
Affinity DataIC50:  1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent