BDBM451161 4-(2-(1-(2-Methoxyphenyl)-5-phenyl-H-pyrazol-3-yl)phenoxy)butanoic acid::US10709688, Example 1::US10709688, Ligand 1

SMILES OC(=O)CCCOc1ccccc1-c1cc(-c2ccccc2Cl)n(n1)-c1ccccc1

InChI Key InChIKey=ZFPJARIXQWTDSX-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 451161   

TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Tohoku University

US Patent
LigandPNGBDBM451161(4-(2-(1-(2-Methoxyphenyl)-5-phenyl-H-pyrazol-3-yl)...)
Affinity DataIC50:  77nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Tohoku University

US Patent
LigandPNGBDBM451161(4-(2-(1-(2-Methoxyphenyl)-5-phenyl-H-pyrazol-3-yl)...)
Affinity DataKd:  627nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Tohoku University

US Patent
LigandPNGBDBM451161(4-(2-(1-(2-Methoxyphenyl)-5-phenyl-H-pyrazol-3-yl)...)
Affinity DataKd:  386nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Tohoku University

US Patent
LigandPNGBDBM451161(4-(2-(1-(2-Methoxyphenyl)-5-phenyl-H-pyrazol-3-yl)...)
Affinity DataIC50:  640nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent