BDBM457 3-({2-tert-butyl-4-[(ethylsulfamoyl)amino]-5-methylphenyl}sulfanyl)-4-hydroxy-6-[2-(4-hydroxyphenyl)ethyl]-6-(propan-2-yl)-5,6-dihydro-2H-pyran-2-one::CHEMBL172271::Dihydropyran-2-one deriv. 62
SMILES CCNS(=O)(=O)Nc1cc(c(SC2C(=O)CC(CCc3ccc(O)cc3)(OC2=O)C(C)C)cc1C)C(C)(C)C
InChI Key InChIKey=SUVOBBUZDNAUIG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 457
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: 1.70nMAssay Description:Activity of potent nonpeptidic inhibitor against proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: 1.70nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair