BDBM458502 2-(2-Fluoro-6-methoxyphenyl)-N-(4-(((3-hydroxyoxetan-3-yl)methyl)(methyl)amino)-1-methyl-1H-indazol-5-yl)pyrimidine-4-carboxamide::US10745388, Example 10

SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1ccc2n(C)ncc2c1N(C)CC1(O)COC1

InChI Key InChIKey=RXTYUQLPDWJECP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 458502   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM458502(2-(2-Fluoro-6-methoxyphenyl)-N-(4-(((3-hydroxyoxet...)
Affinity DataKi:  2.75E+3nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent