BDBM4706 (2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid::2,3-didehydro-2-deoxy-N-acetylneuraminic acid::CHEMBL96712::DANA::Neu5Ac2en

SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

InChI Key InChIKey=JINJZWSZQKHCIP-UFGQHTETSA-N

Data  19 KI  73 IC50

PDB links: 56 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 4706   

TargetSialidase(Clostridium perfringens)
University Of California-Davis

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Clostridium perfringens sialidase using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase B(Streptococcus pneumoniae)
University Of California-Davis

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae sialidase NanC using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetSialidase(Vibrio cholerae)
University Of California-Davis

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of Vibrio cholerae sialidase using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetSialidase-2(Homo sapiens (Human))
University Of California-Davis

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant human cytosolic sialidase NEU2 using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetNeuraminidase NanB(Streptococcus pneumoniae)
University Of California-Davis

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae NanB using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetSialidase A(Streptococcus pneumoniae)
University Of California-Davis

Curated by ChEMBL
LigandPNGBDBM4706((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Streptococcus pneumoniae NanA using Neu5Acalpha2-3GalbetapNP as substrate after 30 mins by colorimetric assayMore data for this Ligand-Target Pair