BDBM477663 N-(4-(chlorodifluoromethoxy)phenyl)-1,2-dimethyl-4-(pyrimidin-5-yl)-1H-benzo[d]imidazole-6-carboxamide::US10889571, Example 4

SMILES Cc1nc2c(cc(cc2n1C)C(=O)Nc1ccc(OC(F)(F)Cl)cc1)-c1cncnc1

InChI Key InChIKey=VGPQMJXNYLLSOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477663   

TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM477663(N-(4-(chlorodifluoromethoxy)phenyl)-1,2-dimethyl-4...)
Affinity DataIC50:  0.270nMAssay Description:ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent