BDBM477804 US10889571, Example 150

SMILES C[C@@H]1CCSc2nc3cc(cc(-c4cncnc4)c3n12)C(=O)Nc1ccc(OC(F)(F)Cl)cc1

InChI Key InChIKey=YUQBVYMLIBOVAS-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477804   

TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM477804(US10889571, Example 150)
Affinity DataIC50:  0.360nMAssay Description:ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent