BDBM480743 N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-1-[2- (hydroxymethyl)-4- pyridyl]pyrazole-3-carboxamide::US10899774, Example 59

SMILES CC1(C)Cc2cc(NC(=O)c3ccn(n3)-c3ccnc(CO)c3)c(cc2O1)N1CCOCC1

InChI Key InChIKey=HPGXWWZKCNHOPR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480743   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM480743(N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-...)
Affinity DataKi:  1.60nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent