BDBM485175 US10934305, Compound HK-1::US10934305, Compound HK-4
SMILES Cc1n[nH]c2OC(N)=C(C#N)C(C3CCC3)(c12)c1cccc(c1)C(F)(F)F
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 485175
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 1.77E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: >5.00E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair