BDBM4862 1-(4-Chloroanilino)-4-(4-pyridylmethyl)-7-aminophthalazine::1-N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazine-1,7-diamine::CGP79787 Analog 45::CHEMBL74143

SMILES Nc1ccc2c(Cc3ccncc3)nnc(Nc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=NMPJZCBLQWVVEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4862   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4862(1-(4-Chloroanilino)-4-(4-pyridylmethyl)-7-aminopht...)
Affinity DataIC50:  650nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM4862(1-(4-Chloroanilino)-4-(4-pyridylmethyl)-7-aminopht...)
Affinity DataIC50:  650nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM4862(1-(4-Chloroanilino)-4-(4-pyridylmethyl)-7-aminopht...)
Affinity DataIC50:  1.70E+3nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed