BDBM4879 1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylmethyl)phthalazine::CGP79787 Analog 64::CHEMBL77555::N-[4-chloro-3-(trifluoromethyl)phenyl]-4-(pyridin-4-ylmethyl)phthalazin-1-amine

SMILES FC(F)(F)c1cc(Nc2nnc(Cc3ccncc3)c3ccccc23)ccc1Cl

InChI Key InChIKey=ONVYCEKKOOSVPA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 4879   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4879(1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylm...)
Affinity DataIC50:  600nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4879(1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylm...)
Affinity DataIC50:  300nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4879(1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylm...)
Affinity DataIC50:  300nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4879(1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylm...)
Affinity DataIC50:  2.70E+3nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4879(1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylm...)
Affinity DataIC50:  4.00E+3nMAssay Description:The autophosphorylation assay was performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified ov...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed