BDBM488540 US10954253, Compound 47::US10954253, Compound 52

SMILES COc1cccc(n1)-n1n(CC=C)c(=O)c2cnc(Nc3ccc(cc3)N3CCC4(CCN(C)CC4)CC3)nc12

InChI Key InChIKey=RMXFSIPIZNPDMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488540   

TargetWee1-like protein kinase(Homo sapiens (Human))
Shijiazhuang Sagacity New Drug Development

US Patent
LigandPNGBDBM488540(US10954253, Compound 47 | US10954253, Compound 52)
Affinity DataIC50:  71nMAssay Description:Experimental Reagents:Basic reaction buffer: 20 mM hydroxyethylpiperazine ethanesulfuric acid (pH 7.5), 10 mM magnesium chloride, 1 mM EGTA, 0.02% Br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWee1-like protein kinase(Homo sapiens (Human))
Shijiazhuang Sagacity New Drug Development

US Patent
LigandPNGBDBM488540(US10954253, Compound 47 | US10954253, Compound 52)
Affinity DataIC50:  3nMAssay Description:Experimental Reagents:Basic reaction buffer: 20 mM hydroxyethylpiperazine ethanesulfuric acid (pH 7.5), 10 mM magnesium chloride, 1 mM EGTA, 0.02% Br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent