BDBM489605 US10961249, Entry 16::US11220505, Entry 7

SMILES CCC1(CC)CC(CCN2CC3CN(CC3C2)c2ccccc2C#N)OC1=O

InChI Key InChIKey=KWYRXGHVMCNABU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489605   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM489605(US10961249, Entry 16 | US11220505, Entry 7)
Affinity DataIC50:  8.90nMAssay Description:A stock concentration of 5 nM [3H]-5-Hydroxytryptamine ([3H]-5HT) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Aliqu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Temple University

US Patent
LigandPNGBDBM489605(US10961249, Entry 16 | US11220505, Entry 7)
Affinity DataIC50:  6.80nMAssay Description:A stock concentration of 5 nM 3H-1,3-di-(2-tolyl)guanidine (3H-DTG) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent