BDBM49376 (6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2-yl)-amine::(6-methyl-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine::MLS000527802::N-(6-methyl-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-(6-methylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::SMR000120376::cid_973018

SMILES Cc1cccc(Nc2nc(cs2)-c2cccs2)n1

InChI Key InChIKey=GNUGUUFOOMYNGW-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 49376   

TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49376((6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2...)
Affinity DataEC50:  1.22E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49376((6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49376((6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49376((6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2...)
Affinity DataIC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49376((6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay