BDBM494220 6-Bromo-N-[2-[(2R)-2- fluoro-3-hydroxy-3-methyl- butyl]-6-morpholino-1-oxo- isoindolin-5- yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 269

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cc(Br)cnc34)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=FSHNCXAQBXJGLH-HXUWFJFHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494220   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM494220(6-Bromo-N-[2-[(2R)-2- fluoro-3-hydroxy-3-methyl- b...)
Affinity DataKi:  1.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent