BDBM494230 N-[6-[4-(2,2- Difluoroethyl)piperazin-1- yl]-2-(3-hydroxy-3-methyl- butyl)-1-oxo-isoindolin-5- yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 279

SMILES CC(C)(O)CCN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCN(CC(F)F)CC1

InChI Key InChIKey=YVBRHDJKKDVOHB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494230   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM494230(N-[6-[4-(2,2- Difluoroethyl)piperazin-1- yl]-2-(3-...)
Affinity DataKi:  1.80nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent