BDBM497130 US11001561, Compound 105::US11702392, Compound 105
SMILES COc1c(F)ccc(c1F)-n1c(C)nc(N2CCC3(Cc4ccccc4[C@H]3N)CC2)c(C)c1=O
InChI Key InChIKey=TXXJSCBQQUEYDL-HSZRJFAPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 497130
Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair