BDBM50005908 CHEMBL3234707::US9062004, 14::US9670216, 14 4-Bromo-5-(2-dimethylaminoethylamino)-2-(3,3,5,5-tetramethylcyclohexyl)pyridazin-3-one

SMILES CN(C)CCNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Br

InChI Key InChIKey=ODCAZILQOIHJAU-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50005908   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataKi:  7.41E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataIC50:  42nMAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataIC50:  42nMT: 2°CAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataEC50:  820nMAssay Description:Agonist activity at CB1 receptor in Swiss Webster mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataIC50:  7.41E+3nMT: 2°CAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005908(CHEMBL3234707 | US9062004, 14 | US9670216, 14 4-Br...)
Affinity DataIC50:  7.41E+3nMAssay Description:Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...More data for this Ligand-Target Pair
In DepthDetails US Patent