BDBM50007659 CHEMBL3233142
SMILES Cc1ccc(cc1)S([O-])(=O)=O.[H][C@]12CC[NH+](CCCC(=O)c3ccc(F)cc3)C[C@@]1([H])c1cccc3N(C)CCN2c13
InChI Key InChIKey=LHAPOGAFBLSJJQ-GUTACTQSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50007659
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 0.540nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of adrenergic alpha1B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]-N-methylspiperone from rat recombinant dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibition of human dopamine D1 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Displacement of [3H]-N-methyl-citalopram from SERT in human platelets after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Inhibition of [3H]-serotonin uptake in SERT in human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Inhibition of adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 1.48E+3nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human recombinant 5HT2A receptor expressed in HEK293a cells assessed as inhibition of serotonin-induced increase in calcium fl...More data for this Ligand-Target Pair