BDBM50007730 CHEMBL3233755
SMILES CC(C)c1cc(C(=O)N2CCc3onc(C(=O)NCCCCCCC(=O)NO)c3C2)c(O)cc1O
InChI Key InChIKey=MSHYQCFSRGHYAU-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50007730
Affinity DataIC50: 33nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human HDAC-6 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 521nMAssay Description:Inhibition of human HDAC-11 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 886nMAssay Description:Inhibition of human HDAC-10 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human HDAC-5 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of human HDAC-4 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human HDAC-1 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human HDAC-7 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 4.23E+3nMAssay Description:Inhibition of human HDAC-3/NCOR-2 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.49E+3nMAssay Description:Inhibition of human HDAC-2 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of human HDAC-8 using RHK(Ac)K(Ac) as substrateMore data for this Ligand-Target Pair