BDBM50008057 BMS-722782::CHEBI:64153::TANESPIMYCIN

SMILES CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O

InChI Key InChIKey=AYUNIORJHRXIBJ-TXHRRWQRSA-N

Data  1 KI  28 IC50  4 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008057   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  140nMAssay Description:Inhibition of GA-FITC binding to human recombinant Hsp90alpha incubated for 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  780nMAssay Description:Displacement of GA-FITC from human recombinant HSP90alpha ATP-binding site by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPutative heat shock protein HSP 90-alpha A4(Homo sapiens (Human))
Shandong University

LigandPNGBDBM50008057(BMS-722782 | CHEBI:64153 | TANESPIMYCIN)
Affinity DataIC50:  780nMpH: 7.3Assay Description:Briefly, reaction mixes (100 µL) containing 20 mM HEPES (pH 7.3), 50 mM KCl, 2 mM DTT, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% Triton X-100 with 0.1 mg/mL B...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed