BDBM50008859 CHEMBL3222141

SMILES Brc1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1

InChI Key InChIKey=IYAYHZZWYNXHEQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50008859   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of SIRT-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human SIRT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of Phosphodiesterase 2 from pig coronary arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.55E+7nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic deacetylase substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of sirtuin 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed