BDBM50010957 2-Methyl-3-{2-[pyridin-3-yl-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-methyl]-phenyl}-acrylic acid::CHEMBL327696

SMILES CC(=Cc1cccc(c1)C(c1cccnc1)=c1c(C)c(O)c(=C)c(C)c1O)C(O)=O

InChI Key InChIKey=YHOKCOIBACOHHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010957   

TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010957(2-Methyl-3-{2-[pyridin-3-yl-(2,4,5-trimethyl-3,6-d...)
Affinity DataIC50:  520nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010957(2-Methyl-3-{2-[pyridin-3-yl-(2,4,5-trimethyl-3,6-d...)
Affinity DataIC50:  1.00E+5nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed