BDBM50011552 CHEMBL3262571::US9592235, Example 168::US9855269, Compound 11

SMILES COc1ccccc1-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=CUSAKFRCIPMPMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011552   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011552(CHEMBL3262571 | US9592235, Example 168 | US9855269...)
Affinity DataIC50:  546nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011552(CHEMBL3262571 | US9592235, Example 168 | US9855269...)
Affinity DataIC50:  751nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011552(CHEMBL3262571 | US9592235, Example 168 | US9855269...)
Affinity DataIC50:  751nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In DepthDetails US Patent