BDBM50011559 CHEMBL3262578::US9592235, Example 269::US9855269, Compound 116

SMILES Nc1ccc(F)c(c1)-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=QJZVASMOYAVXOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011559   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011559(CHEMBL3262578 | US9592235, Example 269 | US9855269...)
Affinity DataIC50:  351nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011559(CHEMBL3262578 | US9592235, Example 269 | US9855269...)
Affinity DataIC50:  174nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50011559(CHEMBL3262578 | US9592235, Example 269 | US9855269...)
Affinity DataIC50:  174nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In DepthDetails US Patent