BDBM50013217 CHEMBL159951::Sodium salt of7-[1-Cyclohexyl-4-(4-fluoro-phenyl)-2-isopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid

SMILES CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1C1CCCCC1)-c1ccc(F)cc1

InChI Key InChIKey=RODBEKUWCLMBSW-FGZHOGPDSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013217   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50013217(CHEMBL159951 | Sodium salt of7-[1-Cyclohexyl-4-(4-...)
Affinity DataIC50:  0.0180nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of hepatic cells (HEP G2, a human hepatoma cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50013217(CHEMBL159951 | Sodium salt of7-[1-Cyclohexyl-4-(4-...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed