BDBM50015270 CHEMBL262958::N-[4-(2-Butyl-4-chloro-5-methoxycarbonylmethyl-imidazol-1-ylmethyl)-phenyl]-phthalamic acid

SMILES CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2ccccc2C(O)=O)cc1

InChI Key InChIKey=VPGBXMVPAQLPJI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50015270   

TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015270(CHEMBL262958 | N-[4-(2-Butyl-4-chloro-5-methoxycar...)
Affinity DataIC50:  420nMAssay Description:Displacement of [125I]-Sar1-Ile8-A II at the rabbit aorta angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015270(CHEMBL262958 | N-[4-(2-Butyl-4-chloro-5-methoxycar...)
Affinity DataIC50:  140nMAssay Description:Binding affinity against angiotensin II receptor type 1 (AT1) from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50015270(CHEMBL262958 | N-[4-(2-Butyl-4-chloro-5-methoxycar...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015270(CHEMBL262958 | N-[4-(2-Butyl-4-chloro-5-methoxycar...)
Affinity DataIC50:  140nMAssay Description:Ability to displace [3H]AII (2 nM) from its specific binding sites in rat adrenal cortical microsome preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015270(CHEMBL262958 | N-[4-(2-Butyl-4-chloro-5-methoxycar...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration that gave 50 percent displacement of specific binding of [3H]AII (2 nM) to Angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed