BDBM50017080 2-{4-[(2,3-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL24701

SMILES Cc1nc2ccc(CN(CC#C)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)cc2c(=O)n1C

InChI Key InChIKey=ZZLZQCHJVCQSAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017080   

TargetThymidylate synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50017080(2-{4-[(2,3-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of purified human thymidylate synthase from a SV40-transformed human fibroblast cell line cloned in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed