BDBM50017203 CHEMBL3287379

SMILES Fc1cc(N2C[C@H](CNc3ccon3)OC2=O)c(F)c(F)c1N1CCC(=O)C=C1

InChI Key InChIKey=SULYVXZZUMRQAX-NSHDSACASA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017203   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Micurx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of MAO-A (unknown origin) using tyramine as substrate after 30 to 60 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Micurx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in yeast after 1 hr by luciferin-based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Micurx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of CYP2E1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed