BDBM50017372 4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-benzoic acid methyl ester::CHEMBL17237

SMILES COC(=O)c1ccc(OCCCN2CCC(CC2)C(O)(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=DNJLISQLMWIPEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017372   

TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
A.H. Robins

Curated by ChEMBL
LigandPNGBDBM50017372(4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-pip...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed