BDBM50019164 CHEMBL1164165

SMILES [O-][N+](=O)c1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=PDSXUXCWTDUVSZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019164   

TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50:  259nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed