BDBM50019953 1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-butan-1-one::CHEMBL59213

SMILES OC1CCN(CCCC(=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=OJTNFBDLVWOHKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019953   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£

Curated by ChEMBL
LigandPNGBDBM50019953(1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-b...)
Affinity DataIC50: >5.00E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetyltransferase Eis(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019953(1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-b...)
Affinity DataIC50:  690nMAssay Description:Inhibition of Mycobacterium tuberculosis Eis assessed as Eis-mediated kanamycin acetylation preincubated for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50019953(1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-b...)
Affinity DataIC50:  5.50E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed