BDBM50021385 CHEMBL3289583

SMILES [#6]-c1ccc(-[#6]-[#7]-[#6](=O)-[#6](-[#6]-[#6]-[#7])-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6](/c2ccccc2)-c2ccccc2)cc1

InChI Key InChIKey=RCURIJNJFSBELZ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50021385   

TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021385(CHEMBL3289583)
Affinity DataKi:  2.95E+4nMAssay Description:Displacement of NO711 from mouse GAT1 expressed in HEK293 cells by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021385(CHEMBL3289583)
Affinity DataIC50:  5.89E+3nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021385(CHEMBL3289583)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021385(CHEMBL3289583)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021385(CHEMBL3289583)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed