BDBM50022529 2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-1-ylmethyl-4-oxo-4-piperidin-1-yl-butyrylamino)-propionylamino]-5-methyl-hexanoic acid methyl ester::CHEMBL159336

SMILES COC(=O)C(O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(CC(=O)N1CCCCC1)Cc1cccc2ccccc12

InChI Key InChIKey=JNHZXGXHSIXVBS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022529   

TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50:  420nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50:  41nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed