BDBM50024210 1H-indole-3-ethanamine::2-(1H-indol-3-yl)ethanamine::2-(3-indolyl)ethylamine::CHEMBL6640::tryptamine

SMILES NCCc1c[nH]c2ccccc12

InChI Key InChIKey=APJYDQYYACXCRM-UHFFFAOYSA-N

Data  74 KI  2 IC50  3 Kd  6 EC50

PDB links: 13 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50024210   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataEC50:  164nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataEC50:  716nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataEC50:  33nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed