BDBM50024836 1,2,3,4-Tetrahydro-isoquinolin-8-ol::CHEMBL69312

SMILES Oc1cccc2CCNCc12

InChI Key InChIKey=UHEOSCFYXMSUPR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50024836   

LigandPNGBDBM50024836(1,2,3,4-Tetrahydro-isoquinolin-8-ol | CHEMBL69312)
Affinity DataKi:  2.15E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50024836(1,2,3,4-Tetrahydro-isoquinolin-8-ol | CHEMBL69312)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50024836(1,2,3,4-Tetrahydro-isoquinolin-8-ol | CHEMBL69312)
Affinity DataKi:  1.08E+6nMAssay Description:In vitro inhibition of bovine phenylethylamine N-methyl-transferase (PNMT) using radiochemical assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed