BDBM50025359 1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid methyl ester::CHEMBL3349116

SMILES [H][C@@]12CC[C@H](C(=O)OC)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2N(C)C(=O)CC[C@]12C

InChI Key InChIKey=IVJOAORQVUYFDW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025359   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025359(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataKi:  165nMAssay Description:Apparent inhibitory constant value for rat prostatic 5-alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50025359(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50025359(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Affinity DataIC50:  120nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed