BDBM50029266 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-isoxazol-3-ylmethyl}-piperidin-2-one; hydrochloride::CHEMBL538529::CHEMBL81093

SMILES CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)no2)CC1

InChI Key InChIKey=DXYQOKKQRDKQCQ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029266   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50029266(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029266(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  94nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029266(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was determined against Dopamine receptor D2 using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50029266(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50029266(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed