BDBM50029603 CHEMBL287919::L-745337::L745,337::N-[6-(2,4-Difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccc(F)cc1F

InChI Key InChIKey=HDUWKQUHMUSICC-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029603   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029603(CHEMBL287919 | L-745337 | L745,337 | N-[6-(2,4-Dif...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029603(CHEMBL287919 | L-745337 | L745,337 | N-[6-(2,4-Dif...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029603(CHEMBL287919 | L-745337 | L745,337 | N-[6-(2,4-Dif...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50029603(CHEMBL287919 | L-745337 | L745,337 | N-[6-(2,4-Dif...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed