BDBM50035837 CHEMBL3359926

SMILES C[C@@]1(CCC[C@H]1Nc1c(cnn2cccc12)C(N)=O)C#N

InChI Key InChIKey=QASDPHCNHAXDKX-IUODEOHRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035837   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035837(CHEMBL3359926)
Affinity DataIC50:  6nMAssay Description:Inhibition of TYK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035837(CHEMBL3359926)
Affinity DataIC50:  15nMAssay Description:Inhibition of JAK1 (unknown origin) bycaliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035837(CHEMBL3359926)
Affinity DataIC50:  10nMAssay Description:Inhibition of JAK3 (unknown origin) by filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035837(CHEMBL3359926)
Affinity DataIC50:  31nMAssay Description:Inhibition of JAK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed