BDBM50036554 CHEMBL3353609

SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1)C(F)(F)F)c1ncc(Cl)cc1Cl

InChI Key InChIKey=CMSUMMIXTLRWFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036554   

TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Raqualia Pharma

Curated by ChEMBL
LigandPNGBDBM50036554(CHEMBL3353609)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at rat TRPM8 assessed as inhibition of menthol induced Ca2+ influx by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Raqualia Pharma

Curated by ChEMBL
LigandPNGBDBM50036554(CHEMBL3353609)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed