BDBM50036932 CHEMBL1478023::US11866416, Compound SN-II-118

SMILES Oc1ccc(\C=C2/Oc3ccccc3C2=O)cc1O

InChI Key InChIKey=HCBULGQMULJTCM-ZSOIEALJSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50036932   

TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Geneva

Curated by ChEMBL
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Geneva

Curated by ChEMBL
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)
Affinity DataIC50:  2.69E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)
Affinity DataIC50:  2.80E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Geneva

Curated by ChEMBL
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)
Affinity DataIC50:  3.08E+3nMAssay Description:Compound was tested for the inhibitory constant for mouse kidney cytidine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University Of Geneva

Curated by ChEMBL
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of HDAC in human HeLa cell extract after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed