BDBM50041276 CHEMBL20302::Methyl-((S)-1-methyl-2-phenyl-ethyl)-phenethyl-amine

SMILES C[C@@H](Cc1ccccc1)N(C)CCc1ccccc1

InChI Key InChIKey=GQJHAVHSZPQZHD-INIZCTEOSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041276   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041276(CHEMBL20302 | Methyl-((S)-1-methyl-2-phenyl-ethyl)...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity towards sigma opioid receptor was determined in guinea pig cerebral homogenate using [3H]haloperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041276(CHEMBL20302 | Methyl-((S)-1-methyl-2-phenyl-ethyl)...)
Affinity DataKi:  6.60nMAssay Description:Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041276(CHEMBL20302 | Methyl-((S)-1-methyl-2-phenyl-ethyl)...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards sigma opioid receptor was determined in rat cerebral homogenate using [3H]haloperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041276(CHEMBL20302 | Methyl-((S)-1-methyl-2-phenyl-ethyl)...)
Affinity DataKi:  16.4nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed