BDBM50045636 3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-oxazolidin-2-one dihydrochloride::CHEMBL2111567

SMILES Cl.Cl.OCCN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1

InChI Key InChIKey=DXUBHXOFLIXZOM-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50045636   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  370nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  230nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50045636(3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  230nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed