BDBM50047316 CHEMBL3314525

SMILES CO[C@H]1CN(CC[C@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl)c1ncc(s1)C(O)=O

InChI Key InChIKey=VJLIVOQJQIHFHR-BDAKNGLRSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50047316   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxin ParE(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataIC50:  910nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ATPase activity of rat Mrp2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataEC50:  7.10E+4nMAssay Description:Stimulation of ATPase activity of human MRP2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ATPase activity of human MRP2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataEC50:  3.80E+4nMAssay Description:Stimulation of ATPase activity of rat Mrp2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxin ParE(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047316(CHEMBL3314525)
Affinity DataIC50:  910nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed