BDBM50048220 CHEMBL35992::N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-indan-5-yl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccccn1

InChI Key InChIKey=URWLQWBEXRFSCD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50048220   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048220(CHEMBL35992 | N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-in...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048220(CHEMBL35992 | N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-in...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048220(CHEMBL35992 | N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-in...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048220(CHEMBL35992 | N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-in...)
Affinity DataIC50:  810nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 activity in U937 microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048220(CHEMBL35992 | N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-in...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 expressed in CHO (chinese hamster ovary) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed